Eivind Valen
Associate professor at the Department of Informatics and the Sars Centre for Marine Molecular Biology, Bergen, Norway
Eivind Valen leads a research group at the Computational Biology Unit and the Sars Centre at the University of Bergen. His lab spans experimental and computational biology and addresses fundamental questions about how genes are regulated.
He obtained his PhD in 2010 from the University of Copenhagen under Albin Sandelin and Anders Krogh, working on transcription initiation and promoter regulation. He later received long-term fellowships from the European Molecular Biology Organization and the Human Frontiers Science Programme and moved to Harvard University and The Broad Institute in Cambridge, Massachusetts. Here, he did a postdoc in the laboratory of Alex Schier studying long non-coding RNAs and micropeptides, and creating tools for CRISPR genome editing. He was subsequently recruited by the Bergen Research Foundation and moved to Norway in 2014. His current focus is on regulation of translation and how the cell prioritizes translation across its transcriptome.
Selected publications
  • Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes.
    Valen E, Preker P, Andersen PR, Zhao X, Chen Y, Ender C, Dueck A, Meister G, Sandelin A, Jensen TH
    Nat Struct Mol Biol, 18 (9), 1075-82 (2011)
  • Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs.
    GL Chew, A Pauli, JL Rinn, A Regev, AF Schier, E Valen
    Development 140 (13), 2828-2834 (2013)
  • CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
    TG Montague, JM Cruz, JA Gagnon, GM Church, E Valen
    Nucleic acids research 42 (W1), W401-W407 (2014)
  • CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering.
    K Labun, TG Montague, JA Gagnon, SB Thyme, E Valen
    Nucleic acids research 44 (W1), W272-W276 (2016)
  • Ribosome signatures aid bacterial translation initiation site identification.
    Giess A, Jonckheere V, Ndah E, Chyzynska K, Van Damme P, Valen E
    BMC Biol, 15 (1), 76 (2017)