Dr. Lorena Arranz leads the research group Stem Cell Aging and Cancer (SAC) at UiT, which performs research within the pathophysiology of stem cells.
Dr. Arranz graduated in Biology (Biomedicine) and obtained her PhD in Physiology at the Universidad Complutense de Madrid (UCM). Under the supervision of Professor Monica De la Fuente, she studied the contribution of fully differentiated myeloid cells to the aging process, with a focus on oxidation and inflammation. The neuro-endocrine regulation of the immune system also grabbed her interest during this period. She performed several short research visits, both at Spanish and international institutions, including the University of Birmingham (UK), the Aarhus University (DK), and the New York University (USA). Her PhD Thesis was awarded as the best presented at the Faculty of Biology (UCM) in 2009.
She then moved to Fundacion Centro Nacional de Investigaciones Cardiovasculares (CNIC) as Postdoctoral Associate. Working in the group of Dr. Simon Mendez-Ferrer, she identified for the first time the critical role played by the haematopoietic stem cell niche in the pathogenesis of the haematological malignancies classified as myeloproliferative neoplasms. This work was published in Nature and received a Merit Award at the congress of the American Society of Hematology (ASH) in 2013. In November 2014, Lorena joined the Department of Medical Biology at the University of Tromsø as Group Leader and NCMM Young Associate Investigator and was appointed as member of the Department of Haematology at the University Hospital of North Norway in January 2015.