MINISYMPOSIA THURSDAY – JANUARY 19TH
- CANCER & CELL BIOLOGY ‘VESLEFJELLHALLEN 1’
Chair: Sissel Rønning
18:00 Development of alphaviral vectors for macrophage activation in cancer immunotherapy
Baiba Kurena
18:15 Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Kirsten Sandvig
18:30 Modeling MLL-rearranged leukemia in Drosophila melanogaster
Helene Knævelsrud
18:45 The first comprehensive time-resolved investigation of glycosphingolipid turnover: Measured by stable-isotope tracer lipidomics
Tore Skotland
19:00 Transcriptional downregulation of cholesterol synthesis pathway genes in prostate cancer
Morten Rye
19.15 Immune Cell Composition in Human Non-Small Cell Lung Cancer
Branislava Stankovic
MINISYMPOSIA THURSDAY – JANUARY 19TH
- STRUCTURAL BIOLOGY ‘VESLEFJELLHALLEN 2’
Chair: Arne Smalås
18:00 Inhibitors can help fighting antibiotic resistance bacteria, but how do we find the best inhibitors?
Hanna-Kirsti S. Leiros
18:15 Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase
Gaston Courtade
18:30 Nanodiscs: tool for NMR lipid/protein structure studies
Martin Jakubec
18:45 Structural insights into TMB-1 (Tripoli metallo-β-lactamase) and the role of residue 119 and 228 in substrate and inhibitor activity
Susann Skagseth
19.00 A research-inspired biochemistry laboratory module – Combining, expression,
purification, crystallisation, structure solving and characterisation of a flavdoxin-like protein.
Hans-Petter Hersleth
19:15 Chitin utilization by Jonesia denitrificans 20603 involves a single bi-catalytic enzyme containing an LPMO and a GH18 domain
Sophanit Mekasha
MINISYMPOSIA THURSDAY – JANUARY 19TH
- BIOTECHNOLOGY ‘VESLEFJELLHALLEN 3’
Chair: Trygve Brautaset
18:00 Making a truly Norwegian salmon
Kiira Vuoristo
18:15 Single-cell analysis using Droplet Digital™ technology
Helge Lind
18:30 Plant biotechnology for low cost production of fish vaccines
Jihong Liu Clarke
18:45 Center for Digital Life Norway –Trans-Disciplinary Biotechnology
Gunnar Dick
19:00 Lactobacillus plantarum as a delivery vehicle for mucosal vaccine against Mycobacterium tuberculosis
Katarzyna Kuczkowska
19.15 SygRNA™-Synthetic Two Part CRISPR RNA System
Marko Sankala
MINISYMPOSIA FRIDAY – JANUARY 20TH
- BIOINFORMATICS ‘VESLEFJELLHALLEN 1’
Chair: Finn Drabløs
14:00 Metabolic characteristics of 361 genomes recovered from the Oslo, EGE biogas
reactor using shotgun metagenomics
John Gaby
14:15 ELIXIR.NO – The national infrastructure for bioinformatics
Finn Drabløs
14:30 A next-generation core facility for Norwegian research: The National Consortium for Sequencing and Personalized Medicine (NCS-PM)
Robert Lyle
14:45 NORBIS – the national research school in bioinformatics, biostatistics and systems biology
Christine Stansberg
15:00 SalmoBase: An integrated molecular data resource for Salmonid species
Jeevan Karloss Antony Samy
15:15 Combination of metagenomics and quantitative metaproteomics highlight the metabolic contributions of uncultured syntrophic phylotypes in a thermophilic anaerobic digester
Live Heldal Hagen
MINISYMPOSIUM FRIDAY – JANUARY 20TH
- EDUCATION IN MOLECULAR LIFE SCIENCES ‘VESLEFJELLHALLEN 2’
Chair: Winnie Eskild
Workshop
14:00 -15.45 Winnie Eskild will introduce the topic with an overview of the activities in this field in Norway and Europe. Anders Goksøyr, Department of Biology, University of Bergen will talk about active learning as it is practiced at University of Bergen. One hour of the symposium is reserved for a practical exercise, which will give the participants a taste of these new approaches to teaching.
MINISYMPOSIA FRIDAY – JANUARY 20TH
- FUNDAMENTAL & APPLIED ENZYMOLOGY I ‘VESLEFJELLHALLEN 3’
Chair: Åsmund Røhr Kjendseth
14:00 Interplay of chemical and enzymatic redox systems during plant biomass degradation by brown-rot fungi
Aniko Varnai
14:15 Thermodynamics of tunnel formation upon substrate binding in a processive glycoside hydrolase
Anne Grethe Hamre
14:30 Bioprospecting of enzymes for processing lignocellulosic biomass
Marianne Slang Jensen
14:45 Norwegian Shipworms and Their Symbionts – Old Enemies Become Allies
Bjørn Altermark
15:00 Enzyme processivity changes with the extent of recalcitrant polysaccharide degradation
Silje Benedicte Lorentzen
15:15 Paradigm-shifting novel insights into the mechanism of Lytic Polysaccharide Monooxygenases
Bastien Bissaro
MINISYMPOSIA FRIDAY – JANUARY 20TH
- CHROMATIN & EPIGENETICS ‘VESLEFJELLHALLEN 1
Chair: Pål Falnes
16:30 Identification and characterisation of lysine-specific methyltransferases
in humans
Pål Falnes
16:45 Characterization of novel lysine specific methyltransferase that induces
dynamic methylation in human eukaryotic elongation factor 1 alpha (eEF1A)
Jedrzej Malecki
17:00 CW-domain Specificity and Function in Histone-tail Recognizing Proteins
Maxim Bril’kov
17:15 A novel role of the DNA glycosylase MPG in regulation of epigenetic modifications after alkylation damage
Karine Bjørås
17:30 hSMUG1 is a bi-functional DNA glycosylase
Marina Alexeeva
17:45 Alkyladenine DNA glycosylase on the interface of base excision repair and transcription
Nicola Pietro Montaldo
MINISYMPOSIA FRIDAY – JANUARY 20TH
- MICROBIOLOGY I ‘VESLEFJELLHALLEN 2’
Chair: Dzung Diep
16:30 A stable core gut microbiota across fresh- to saltwater transition for farmed Atlantic salmon
Knut Rudi
16:45 Is there a personal core microbiota?
Ekaterina Avershina
17:00 Rearing water treatment influences the microbiota and transcript profiles of cod larvae.
Ragnhild I. Vestrum
17:15 Regulation of horizontal gene transfer by the conserved response regulator CtrA
AB Westbye
17:15 Secretion and precision surface display of heterologous proteins in Lactobacillus
Geir Mathiesen
17:30 The seasonal change of the gut mycobiota in honey bee Apis mellifera
Åsmund Andersen
MINISYMPOSIA FRIDAY – JANUARY 20TH
- FUNCTIONAL GENOMICS & BIOINFORMATICS I ‘VESLEFJELLHALLEN 3’
Chair: Simen Rød Sandve
16:30 Genetic interaction between core and accessory Non-homologous DNA end joining factors
Mengtan Xing
16:45 Inhibition of mutagenesis by targeting the DNA sliding clamps, PCNA and b-clamp
Synnøve Brandt Ræder
17:00 Non-homologous end joining factors PAXX and XLF in murine B lymphocyte development and human cells
Alisa Dewan
17:15 Repair of double methylated bases in DNA
Almaz Nigatu Tesfahun
17:30 A deeper look into DNA repair mechanism in single molecule level
Arash Ahmadi
17:45 DNA methylation at enhancers distinguishes distinct breast cancer lineages
Vessela Kristensen
MINISYMPOSIA SATURDAY – JANUARY 21st
- FUNDAMENTAL & APPLIED ENZYMOLOGY II ‘VESLEFJELLHALLEN 1
Chair: Jon Nissen-Meyer
15:00 Crystal structures of bacterial enterotoxins in complex with GM1 inhibitors: towards new cholera prophylactics and treatment
Julie E. Heggelund
15:15 Opening Pandora’s Box of Analytics; Analyzing Oxidized Sugars
Bjørge Westereng
15:30 New iminodiacetate-thiosemicarbazone hybrids and their copper(II) complexes are potential mR2 RNR inhibitors with high antiproliferative activity
Marta Hammerstad
15:45 Activation of the Class Ib Ribonucleotide Reductase by a Flavodoxin Reductase in Bacillus cereus
Ingvild Gudim
16:00 Computational study of the protonation states of the conserved HIS172 in the lytic polysaccharide monooxygenase ScLPMO10B
Ingvild Isaksen
16:15 How oxidative carbohydrate cleaving enzymes orient and locate their spot on crystalline substrate
Åsmund Kjendseth Røhr
MINISYMPOSIA SATURDAY – JANUARY 21st
- MICROBIOLOGY II ‘VESLEFJELLHALLEN 2’
Chair: Ida Rud
15:00 Uncultured Bacteroidetes populations inherent to the cow rumen microbiome reveal novel cellulose-degrading mechanisms
Adrian Naas
15:15 A Complex Catalytic Apparatus Confers Mannan Metabolism in the Human Colonic Bacterium Roseburia intestinalis
Sabina Leanti La Rosa
15:30 Susceptibility to inflammation-induced intestinal carcinogenesis in A/J Min/+ mice is dependent on the intestinal microbiota
Ida Rud
15:45 Effects of an antibiotic resistant bacteria on the gut microbiota composition; an in vivo study, using a honeybee model.
Jane Ludvigsen
16:00 Bacterial secretomes after growth on chitin – can we get the true secretomes?
Tina R. Tuveng
16:15 The Atlantic salmon (Salmo salar) skin microbiome and its role in degradation of mucus components
Giusi Minniti
16:30 Trimeric Autotransporter Adhesins (TAAs) and strategies for their inhibition
Dirk Linke
MINISYMPOSIA SATURDAY – JANUARY 21st
- FUNCTIONAL GENOMICS & BIOINFORMATICS II ‘VESLEFJELLHALLEN 3’
Chair: Thorsten Hamann
15:00 A composite mechanism maintains plant cell wall integrity in Arabidopsis thaliana
Thorsten Hamann
15:15 Plant cell wall surveillance: Networking to monitor and maintain integrity
Timo Engelsdorf
15:30 DNA Damage and Repair, Plant Comets Tell a Story
John Einset
15:45 Looking through the glass: Gene expression and regulation of Silicon metabolism in the diatom Thalassiosira pseudonana under Si shift-up and shift-down conditions
Tore Brembu
16:00 Glucosinolate hydrolysis products as danger signals in Arabidopsis thaliana
Ane Kjersti Vie
16:15 Combined inactivation of two acetyltransferases abrogates B lymphocyte development
Valentyn Oksenych
16.30 A germline homozygous mutation in human Oxidation Resistance 1 gene cause developmental delay, epilepsy and cerebellar atrophy
Xiaolin Lin