NBS Bergen Julemøte 2022 – Prof. Anni Vedeler

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NBS Bergen is happy to invite you all to the NBS Bergen Christmas Meeting and General Assembly, on Tuesday Nov. 29th at 16.00 at the Department of Biomedicine, UiB. There will be a scientific presentation from Prof. Anni Vedeler, Dep of Biomedicine, UiB. Pizza and refreshments will be served.

The Lipid-Binding Protein Annexin A2 in the RNA world

The regulation of intracellular functions in mammalian cells involves close coordination of cellular processes. During the recent years it has become evident that the sorting, trafficking and distribution of transport vesicles and mRNA granules/complexes are coordinated to minimize the use of cellular energy and ensure effective simultaneous handling of all components required for a specific function. Identification of specific proteins that act at the crossroads of such coordinated transport events will ultimately provide mechanistic details of the processes. Annexins are multi-functional proteins involved in a variety of cellular processes associated with Ca2+-regulation and lipid binding, linked to operation of both the endocytic and exocytic pathways. Furthermore, Annexins bind specific mRNAs and is involved in the regulation of mRNA transport and translation. The combined RNA- and lipid-binding properties of the Annexins make them attractive candidates to participate in coordinated transport of membrane vesicles and mRNAs regulated by Ca2+.

The BRCA2/RAD51 axis is required to protect cells against transcription-replication conflicts

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NBS invites you all to the second NBS online seminar of 2022! The seminar series is a collaboration between all local NBS branches with talks by researchers from Bergen, Oslo, Trondheim, Tromsø and Ås. The seminar will be held on zoom and is open for all. This month we are proud to present a talk by Prof. Ian Hickson from the University of Copenhagen, Denmark. Prof. Hickson is director of the Center for Chromosome Stability at UCPH and will give a talk about the BRCA2/RAD51 axis and transcription-replication conflicts:

Tuesday June 7th at 11.00 (Open for all!)

Zoom webinar: https://uio.zoom.us/j/7801877377

NBS Online Seminar Series – April 26th at 14.30 | NAD replenishment therapy for Parkinsons disease: from the bench to the bedside

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NBS invites you all to the national NBS Seminar series! The seminar series is a collaboration between all local NBS branches with talks by researchers from Oslo, Bergen, Trondheim, Tromsø and Ås. The seminar will be held on zoom and is open for all!

Title: NAD replenishment therapy for Parkinson’s disease: from the bench to the bedside
Speaker: Charalampos Tzoulis, Department of Neurology, UiB

Tuesday April 26th at 14.30 (Open for all!)
Zoom Meeting ID: 662 5637 2254
Passcode: 39692239

Link to zoom meeting → https://uib.zoom.us/j/66256372254?pwd=TTdhV2lTTjIyUmszZGZDTUNaN3VDZz09

Parkinson’s disease is one of the most common neurodegenerative disorders, affecting approximately 1-2% of the population above 65 years of age. The disease is characterized by the formation of Lewy bodies, death of dopaminergic neurons in a part of the brain called substantia nigra, and a corresponding loss of dopamine signaling. There is no cure for Parkinson’s disease, and all treatment options are symptomatic treatments with no effect on disease progression.

Charalampos Tzoulis is a Professor of Neurology and Neurogenetics at the University of Bergen and Haukeland University Hospital, and an expert on movement disorders and neurodegeneration, including dementia and parkisonism. His research focuses on exploring the role of mitochondrial dysfunction in Parkinson’s disease (PD) with the aim to improve patient diagnosis and develop neuroprotective therapies.

Charalampos Tzoulis is the Principal Investigator of the research group Neuromics at the University of Bergen and co-Director of the Neuro-SysMed Center of Excellence for Clinical Research in Neurological diseases, where he leads the research on PD and are running two clinical trials aimed at improving treatment for patients with Parkinson’s disease. Since 2022, he is also the Director of the K.G. Jebsen Center for Translational Research in Parkinson’s Disease at UiB.