Topic: The role of histone acetylation and other histone modifications in enhancer function.
A position as postdoctoral fellow in molecular biology is vacant at the Department of Molecular Biology (www.uib.no/en/mbi). The position is for a period of 3 years and is funded by the Norwegian Cancer Society. The position is associated with the group of professor Rein Aasland and is part of the intradepartmental research programme NucReg which focuses on molecular interactions, their regulation and function in relation to gene regulation and transcriptional responses. (http://www.uib.no/en/rg/nucreg and http://www.uib.no/en/mbi).
About the project
Topic for the project is the molecular mechanisms for enhancer function in the context of regulation of gene expression in normal cells and during development of cancer. The role of histone acetylation and other histone modifications in the communication between enhancers and promoters is a key question. The project builds on data from a proteomic screen which implicates several protein complexes and new proteins in enhancer function. Approaches in the project will include CRISPR/Cas9, ChIP, and knock-down).
Qualification requirements include:
- The applicant must hold a Norwegian PhD or an equivalent degree within molecular biology or molecular cell biology or have submitted his/her doctoral thesis for assessment prior to the application deadline. It is a condition for employment that the PhD has been awarded.
- Successful applicants must have experience with cell culture and genetic engineering. Experience with modern molecular genetic methods will be emphasized.
- Interest for and experience with research on gene regulation or chromatin is an advantage.
Please consult the full advertisement of the position on Jobbnorge.no and observe that only applications submitted through this website are accepted https://www.jobbnorge.no/en/available-jobs/job/120751
Deadline: January 26th 2016